Endocrine Abstracts

Chronic hypovolemic hyponatriemia is typical for Addisonian crisis and may provoke brain edema but its rapid correction may lead to myelinolysis. We report 2 newly diagnosed cases of primary adrenal insufficiency (PAI) associated with severe hyponatriemia which correction was complicated by osmotic myelinolysis.Case 1: Twenty four-year-old female was admitted with vomiting, sopor, shock. Serum sodium was 83, glucosae 3.6 mmol/l. Serum cortisol 34 nmol/l ...

Aim: To present a case of severe primary hyperparathyroidism (PHPT) manifested predominantly with polyuria.Case: A 53 years old caucasian female presented to the emergency room with polyuria (5-6 l), and increasing during last 4 weeks dehydration, weight loss (10 kg), weakness, confusion. Diabetes mellitus and insipidus had been excluded. After hypercalcemia (3.6–3.9 mmol\l), Ca++ to 2.0 mmol\l and PTH of 616 pg\ml (11–62) were revealed acute P...